Effective removal of the antibiotic Nafcillin from water by combining the Photoelectro-Fenton process and Anaerobic Biological Digestion

J. Vidal, C. Huiliñir, R. Santander, J. Silva-Agredo, R.A. Torres-Palma, R. Salazar

Research output: Contribution to journalArticle

  • 3 Citations

Abstract

The elimination of the antibiotic Nafcillin (NAF), which is usually used in hospitals and veterinary clinics around the world, was assessed through a combination of three advanced electrochemical oxidation processes followed by anaerobic digestion process. In the first stage different electrochemical advanced oxidation processes (EAOPs) were used: electro-oxidation with hydrogen peroxide (EO-H2O2), electro-Fenton (EF) and Photo electro-Fenton (PEF). After PEF, almost complete and highly efficient degradation and elimination of NAF was achieved, with the concomitant elimination of the associated antimicrobial activity. The fast degradation rate produced by PEF is explained by the oxidative action of hydroxyl radicals (•OH) together with the direct UV photolysis of complexes formed between Fe3 + and some organic intermediates. Total removal of NAF occurs after 90 min of electrolysis by PEF, with the generation of organic intermediates that remain in solution. However, when this post PEF process solution was treated with an anaerobic biological process, the intermediates generated in the electrochemical degradation of NAF were completely eliminated after 24 h. The kinetic degradation of NAF as well as the identification/quantification of products and intermediates formed during the degradation of antibiotic, such as inorganic ions, carboxylic acids and aromatic compounds, were determined by chromatographic and photometric methods. Finally, an oxidation pathway is proposed for the complete conversion to CO2. © 2017
LanguageEnglish
Pages1095-1105
Number of pages11
JournalScience of the Total Environment
Volume624
DOIs
Publication statusPublished - 2018

Fingerprint

Nafcillin
Antibiotics
antibiotics
digestion
Anti-Bacterial Agents
Degradation
degradation
Water
oxidation
water
Oxidation
Anaerobic digestion
antimicrobial activity
Aromatic compounds
Electrooxidation
Electrochemical oxidation
Photolysis
carboxylic acid
hydroxyl radical
Carboxylic Acids

Keywords

  • Anaerobic digestion
  • Antimicrobial activity
  • Degradation
  • Hydroxyl radical
  • Livestock industry
  • Nafcillin
  • Photoelectro-Fenton process
  • Agriculture
  • Antibiotics
  • Coal tar
  • Electrochemical oxidation
  • Electrooxidation
  • Iron alloys
  • Microorganisms
  • Oxidation
  • Oxidation resistance
  • Photodegradation
  • Photolysis
  • Anaerobic digestion process
  • Anti-microbial activity
  • Electrochemical advanced oxidation process
  • Electrochemical degradation
  • Hydroxyl radicals
  • Organic intermediates
  • hydrogen peroxide
  • nafcillin
  • anaerobic digestion
  • antibiotics
  • antimicrobial activity
  • degradation
  • electrochemistry
  • electrokinesis
  • hydroxyl radical
  • livestock
  • oxidation
  • photolysis
  • pollutant removal
  • water pollution
  • Article
  • chemical reaction
  • controlled study
  • degradation kinetics
  • electrolysis
  • mineralization
  • oxidation kinetics
  • photoelectro Fenton process
  • priority journal
  • quantitative analysis
  • ultraviolet radiation
  • waste component removal

Cite this

Effective removal of the antibiotic Nafcillin from water by combining the Photoelectro-Fenton process and Anaerobic Biological Digestion. / Vidal, J.; Huiliñir, C.; Santander, R.; Silva-Agredo, J.; Torres-Palma, R.A.; Salazar, R.

In: Science of the Total Environment, Vol. 624, 2018, p. 1095-1105.

Research output: Contribution to journalArticle

@article{73a47d14f3a44516a16f039a5f76def4,
title = "Effective removal of the antibiotic Nafcillin from water by combining the Photoelectro-Fenton process and Anaerobic Biological Digestion",
abstract = "The elimination of the antibiotic Nafcillin (NAF), which is usually used in hospitals and veterinary clinics around the world, was assessed through a combination of three advanced electrochemical oxidation processes followed by anaerobic digestion process. In the first stage different electrochemical advanced oxidation processes (EAOPs) were used: electro-oxidation with hydrogen peroxide (EO-H2O2), electro-Fenton (EF) and Photo electro-Fenton (PEF). After PEF, almost complete and highly efficient degradation and elimination of NAF was achieved, with the concomitant elimination of the associated antimicrobial activity. The fast degradation rate produced by PEF is explained by the oxidative action of hydroxyl radicals (•OH) together with the direct UV photolysis of complexes formed between Fe3 + and some organic intermediates. Total removal of NAF occurs after 90 min of electrolysis by PEF, with the generation of organic intermediates that remain in solution. However, when this post PEF process solution was treated with an anaerobic biological process, the intermediates generated in the electrochemical degradation of NAF were completely eliminated after 24 h. The kinetic degradation of NAF as well as the identification/quantification of products and intermediates formed during the degradation of antibiotic, such as inorganic ions, carboxylic acids and aromatic compounds, were determined by chromatographic and photometric methods. Finally, an oxidation pathway is proposed for the complete conversion to CO2. {\circledC} 2017",
keywords = "Anaerobic digestion, Antimicrobial activity, Degradation, Hydroxyl radical, Livestock industry, Nafcillin, Photoelectro-Fenton process, Agriculture, Antibiotics, Coal tar, Electrochemical oxidation, Electrooxidation, Iron alloys, Microorganisms, Oxidation, Oxidation resistance, Photodegradation, Photolysis, Anaerobic digestion process, Anti-microbial activity, Electrochemical advanced oxidation process, Electrochemical degradation, Hydroxyl radicals, Organic intermediates, hydrogen peroxide, nafcillin, anaerobic digestion, antibiotics, antimicrobial activity, degradation, electrochemistry, electrokinesis, hydroxyl radical, livestock, oxidation, photolysis, pollutant removal, water pollution, Article, chemical reaction, controlled study, degradation kinetics, electrolysis, mineralization, oxidation kinetics, photoelectro Fenton process, priority journal, quantitative analysis, ultraviolet radiation, waste component removal",
author = "J. Vidal and C. Huili{\~n}ir and R. Santander and J. Silva-Agredo and R.A. Torres-Palma and R. Salazar",
note = "Cited By :1 Export Date: 11 April 2018 CODEN: STEVA Correspondence Address: Vidal, J.; Laboratorio de Electroqu{\'i}mica del Medio Ambiente (LEQMA), Departamento de Qu{\'i}mica de los Materiales, Facultad de Qu{\'i}mica y Biolog{\'i}a, Universidad de Santiago de Chile (USACH), Casilla 40, Correo 33, Chile Chemicals/CAS: hydrogen peroxide, 7722-84-1; nafcillin, 147-52-4, 985-16-0 Funding details: 111565842980, COLCIENCIAS, Departamento Administrativo de Ciencia, Tecnolog{\'i}a e Innovaci{\'o}n Funding details: 1170352, FONDECYT, Fondo Nacional de Desarrollo Cient{\'i}fico y Tecnol{\'o}gico Funding text: The authors thank the financial support of FONDECYT Grant 1170352, DICYT-USACH, CONICYT FONDEQUIP/UHPLC-MS/MS EQM 120065 and to COLCIENCIAS project “Desarrollo y evaluaci{\'o}n de un sistema electroqu{\'i}mico asistido con luz solar para la eliminaci{\'o}n de contaminantes emergentes en agua (No. 111565842980 Convocatoria 658, 2014). J. Vidal thanks CONICYT for the National PhD scholarship 21140248 and Pacific Alliance Scholarship. Finally, we are grateful to “Proyectos Basales y Vicerrector{\'i}a de Investigaci{\'o}n, Desarrollo e Innovaci{\'o}n”, 021742SG_PUBLIC. References: Almeida, L.C., Garc{\'i}a-Segura, S., Arias, C., Bocchi, N., Brillas, E., Electrochemical mineralization of the azo dye Acid Red 29 (Chromotrope 2R) by photoelectro – Fenton process (2012) Chemosphere, 89, pp. 751-758; Amaral, F.M., Kato, M.T., Florencio, L., Gavazza, S., Color, organic matter and sulfate removal from textile effluents by anaerobic and aerobic processes (2014) Bioresour. Technol., 163, pp. 364-369; APHA, AWWA, WPCF, Standard Methods for the Examination of Water and Wastewater (2012), 22th edition APHA Washington, D.C; Benito, A., Penad{\'e}s, A., Lliberia, J.L., Gonzalez-Olmos, R., Degradation pathways of aniline in aqueous solutions during electro-oxidation with BDD electrodes and UV/H2O2 treatment (2017) Chemosphere, 166, pp. 230-237; Brillas, E., Mart{\'i}nez-Huitle, C.A., Decontamination of wastewaters containing synthetic organic dyes by electrochemical methods. An updated review (2015) Appl. Catal. B Environ., 166-167, pp. 603-643; Brillas, E., Sires, I., Oturan, M., Electro-Fenton process and related electrochemical technologies based on Fenton's reaction chemistry (2009) Chem. Rev., 109 (12), pp. 6570-6631; Chiavola, A., Farabegoli, G., Antonetti, F., Biological treatment of olive mill wastewater in a sequencing batch reactor (2014) Biochem. Eng. J., 85, pp. 71-78; Clesceri, L., Greenberg, A., Eaton, A., Standard Methods for Examination of Water & Wastewater. 21st edici{\'o}n (2005); El-Ghenymy, A., Cabot, P.L., Centellas, F., Garrido, J.A., Rodr{\'i}guez, R.M., Arias, C., Brillas, E., Mineralization of sulfanilamide by electro-Fenton and solar photoelectro-Fenton in a pre-pilot plant with a Pt/air-diffusion cell (2013) Chemosphere, 91, pp. 1324-1331; El-Ghenymy, A., Centellas, F., Rodr{\'i}guez, R.M., Cabot, P.L., Garrido, J.A., Sir{\'e}s, I., Brillas, E., Comparative use of anodic oxidation, electro-Fenton and photoelectro-Fenton with Pt or boron-doped diamond anode to decolorize and mineralize Malachite Green oxalate dye (2015) Electrochim. Acta, 182, pp. 247-256; Espinoza, C., Romero, J., Villegas, L., Cornejo-Ponce, L., Salazar, R., Mineralization of the textile dye acid yellow 42 by solar photoelectro-Fenton in a lab-pilot plant (2016) J. Hazard. Mater., 319, pp. 24-33; Garc{\'i}a-Rodr{\'i}guez, O., Ba{\~n}uelos, J.A., El-Ghenymy, A., God{\'i}nez, L.A., Brillas, E., Rodr{\'i}guez-Valadez, F.J., Use of a carbon felt–iron oxide air-diffusion cathode for the mineralization of Malachite Green dye by heterogeneous electro-Fenton and UVA photoelectro-Fenton processes (2016) J. Electroanal. Chem., 767, pp. 40-48; Garc{\'i}a-Segura, S., Salazar, R., Brillas, E., Mineralization of phthalic acid by solar photoelectro-Fenton with a stirred boron-doped diamond/air-diffusion tank reactor: influence of Fe3 + and Cu2 + catalysts and identification of oxidation products (2013) Electrochim. Acta, 113, pp. 609-619; Garc{\'i}a-Segura, S., Vieira dos Santos, E., Mart{\'i}nez-Huitle, C.A., Role of sp3/sp2 ratio on the electrocatalytic properties of boron-doped diamond electrodes: a mini review (2015) Electrochem. Commun., 59, pp. 52-55; Garc{\'i}a-Segura, S., Brillas, E., Cornejo-Ponce, L., Salazar, R., Effect of the Fe3 +/Cu2 + ratio on the removal of the recalcitrant oxalic and oxamic acids by electro-Fenton and solar photoelectro-Fenton (2016) Sol. Energy, 124, pp. 242-253; Garc{\'i}a-Segura, S., Anotai, J., Singhadech, S., Lu, M.-C., Enhancement of biodegradability of o-toluidine effluents by electro-assisted photo-Fenton treatment (2017) Process Saf. Environ. Prot., 106, pp. 60-67; Giraldo-Aguirre, L., Erazo-Erazo, E.D., Fl{\'o}rez-Acosta, O.A., Serna-Galvis, E.A., Torres-Palma, R.A., TiO2 photocatalysis applied to the degradation and antimicrobial activity removal of oxacillin: evaluation of matrix components, experimental parameters, degradation pathways and identification (2015) J. Photochem. Photobiol. A Chem., 311, pp. 95-103; Ikumi, S., Harding, T.H., Ekama, G.A., Biodegradability of wastewater and activated sludge organics in anaerobic digestion (2014) Water Res., 56, pp. 267-279; Inyang, M., Flowers, R., McAvoy, D., Dickenson, E., Biotransformation of trace organic compounds by activated sludge from a biological nutrient removal treatment system (2016) Bioresour. Technol., 216, pp. 778-784; Katzung, B.G., Masters, S.B., Trevor, A.J., Farmacolog{\'i}a B{\'a}sica y Cl{\'i}nica (2013), 12th edici{\'o}n Mc Graw Hill; Kemper, N., Veterinary antibiotics in the aquatic and terrestrial environment (2008) Ecol. Indic., 8, pp. 1-13; Kim, K.-S., Yang, C.-S., Mok, Y.S., Degradation of veterinary antibiotics by dielectric barrier discharge plasma (2013) Chem. Eng. J., 219, pp. 19-27; Kummerer, K., The presence of pharmaceuticals in the environment due to human use-present knowledge and future challenges (2009) J. Environ. Manag., 90, pp. 2354-2366; Markis, F., Baudez, J.C., Parthasarathy, R., Slatter, P., Eshtiaghi, N., Rheological characterization of primary and secondary sludge: impact of solids concentration (2014) Chem. Eng. J., 47, pp. 5493-5510; Mart{\'i}nez-Huitle, C.A., Rodrigo, M.A., Sires, I., Scialdone, O., Single and coupled electrochemical processes and reactors for the abatement of organic water pollutants: a critical review (2015) Chem. Rev., 115, pp. 13362-13407; Montalvo, S., Lorna, G., Tratamiento anaerobio de residuos. Universidad T{\'e}cnica Federico Santa Mar{\'i}a 1st edition (2003); Moreira, F.C., Boaventura, R.A.R., Brillas, E., Vilar, V.J.P., Remediation of a winery wastewater combining aerobic biological oxidation and electrochemical advanced oxidation processes (2015) Water Res., 75, pp. 95-108; Olvera-Vargas, H., Oturan, N., Oturan, M.A., Brillas, E., Electro-Fenton and solar photoelectro-Fenton treatments of the pharmaceutical ranitidine in pre-pilot flow plant scale (2015) Sep. Purif. Technol., 146, pp. 127-135; Pereira, G.F., El-Ghenymy, A., Thiam, A., Carlesi, C., Eguiluz, K.I.B., Salazar-Banda, G.R., Brillas, E., Effective removal of Orange-G azo dye from water by electro-Fenton and photoelectro-Fenton processes using a boron-doped diamond anode (2016) Sep. Purif. Technol., 160, pp. 145-151; P{\'e}rez, J.F., Llanos, J., S{\'a}ez, C., L{\'o}pez, P., Ca{\~n}izares, P., Rodrigo, M.A., Treatment of real effluents from the pharmaceutical industry: a comparison between Fenton oxidation and conductive-diamond electro-oxidation (2017) J. Environ. Manag., 195, pp. 216-223; Pignatello, J.J., Oliveros, E., MacKay, A., Advanced oxidation processes for organic contaminant destruction based on the Fenton reaction and related chemistry (2006) Crit. Rev. Environ. Sci. Technol., 36, pp. 1-84; Pipi, A.R.F., Sir{\'e}s, I., De Andrade, A.R., Brillas, E., Application of electrochemical advanced oxidation processes to the mineralization of the herbicide diuron (2014) Chemosphere, 109, pp. 49-55; Raschitor, J., Llanos, J., Ca{\~n}izares, P., Rodrigo, M.A., Novel integrated electroidialysis/electro-oxidation process for the efficient degradation of 2,4 – dichlorophenoxyacetic acid (2017) Chemosphere, 182, pp. 85-89; Ruiz, E.J., Arias, C., Brillas, E., Hern{\'a}ndez-Ram{\'i}rez, A., Peralta-Hern{\'a}ndez, J.M., Mineralization of acid yellow 36 azo dye by electro-Fenton and solar photoelectro-Fenton processes with a boron-doped diamond anode (2011) Chemosphere, 82, pp. 495-501; Salazar, R., Garc{\'i}a-Segura, S., Ureta-Za{\~n}artu, M.S., Brillas, E., Degradation of disperse azo dyes from waters by solar photoelectro-Fenton (2011) Electrochim. Acta, 56, pp. 6371-6379; Salazar, C., Contreras, N., Mansilla, H.D., Y{\'a}nez, J., Salazar, R., Electrochemical degradation of the antihypertensive losartan inaqueous medium by electro-oxidation with boron-doped diamondelectrode (2016) J. Hazard. Mater., 319, pp. 84-92; Serna-Galvis, E.A., Silva-Agredo, J., Giraldo-Aguirre, A.L., Torres-Palma, R.A., Sonochemical degradation of the pharmaceutical fluoxetine: effect of parameters, organic and inorganic additives and combination with a biological system (2015) Sci. Total Environ., 525, pp. 354-360; Serna-Galvis, E.A., Silva-Agredo, J., Giraldo-Aguirre, A.L., Fl{\'o}rez-Acosta, O.A., Torres-Palma, R.A., Comparative study of the effect of pharmaceutical additives on the elimination of antibiotic activity during the treatment of oxacillin in water by the photo-Fenton, TiO2-photocatalysis and electrochemical processes (2016) Sci. Total Environ., 541, pp. 1431-1438; Serna-Galvis, E.A., Silva-Agredo, J., Giraldo-Aguirre, A.L., Fl{\'o}rez-Acosta, O.A., Torres-Palma, R.A., High frequency ultrasound as a selective advanced oxidation process to remove penicillinic antibiotics and eliminate its antimicrobial activity from water (2016) Ultrason. Sonochem., 31, pp. 276-283; Sir{\'e}s, I., Brillas, E., Electrochemical removal of pharmaceuticals from water streams: reactivity elucidation by mass spectrometry (2016) TrAC Trends Anal. Chem., 70, pp. 112-121; Thiam, A., Sir{\'e}s, I., Brillas, E., Treatment of a mixture of food color additives (E122, E124 and E129) in different water matrices by UVA and solar photoelectron-Fenton (2015) Water Res., 81, pp. 178-187; Trellu, C., P{\'e}chaud, Y., Oturan, N., Mousset, E., Huguenot, D., van Hullebusch, E.D., Esposito, G., Oturan, M.A., Comparative study on the removal of humic acids from drinkingwater by anodic oxidation and electro-Fenton processes: mineralization efficiency and modelling (2016) Appl. Catal. B Environ., 194, pp. 32-41; Urz{\'u}a, J., Gonz{\'a}lez-Vargas, C., Sep{\'u}lveda, F., Ureta-Za{\~n}artu, M.S., Salazar, R., Degradation of conazole fungicides in water by electrochemical oxidation (2013) Chemosphere, 93, pp. 2774-2781; Vidal, J., Huili{\~n}ir, C., Salazar, R., Removal of organic matter contained in slaughterhouse wastewater using a combination of anaerobic digestion and solar photoelectro-Fenton processes (2016) Electrochim. Acta, 210, pp. 163-170; Wang, A., Li, Y.-Y., Ledezma Estrada, A., Mineralization of antibiotic sulfamethoxazole by photoelectron-Fenton treatment using activated carbon filter cathode and under UVA irradiation (2011) Appl. Catal. B Environ., 102, pp. 378-386; Zhou, Y., Zhang, J., Zhang, Z., Zhou, C., Lai, Y.S., Xia, S., Enhanced performance of short-time aerobic digestion for waste activated sludge under the presence of cocoamidopropyl betaine (2017) Chem. Eng. J., 320, pp. 494-500",
year = "2018",
doi = "10.1016/j.scitotenv.2017.12.159",
language = "English",
volume = "624",
pages = "1095--1105",
journal = "Science of the Total Environment",
issn = "0048-9697",
publisher = "Elsevier Science B.V.",

}

TY - JOUR

T1 - Effective removal of the antibiotic Nafcillin from water by combining the Photoelectro-Fenton process and Anaerobic Biological Digestion

AU - Vidal, J.

AU - Huiliñir, C.

AU - Santander, R.

AU - Silva-Agredo, J.

AU - Torres-Palma, R.A.

AU - Salazar, R.

N1 - Cited By :1 Export Date: 11 April 2018 CODEN: STEVA Correspondence Address: Vidal, J.; Laboratorio de Electroquímica del Medio Ambiente (LEQMA), Departamento de Química de los Materiales, Facultad de Química y Biología, Universidad de Santiago de Chile (USACH), Casilla 40, Correo 33, Chile Chemicals/CAS: hydrogen peroxide, 7722-84-1; nafcillin, 147-52-4, 985-16-0 Funding details: 111565842980, COLCIENCIAS, Departamento Administrativo de Ciencia, Tecnología e Innovación Funding details: 1170352, FONDECYT, Fondo Nacional de Desarrollo Científico y Tecnológico Funding text: The authors thank the financial support of FONDECYT Grant 1170352, DICYT-USACH, CONICYT FONDEQUIP/UHPLC-MS/MS EQM 120065 and to COLCIENCIAS project “Desarrollo y evaluación de un sistema electroquímico asistido con luz solar para la eliminación de contaminantes emergentes en agua (No. 111565842980 Convocatoria 658, 2014). J. Vidal thanks CONICYT for the National PhD scholarship 21140248 and Pacific Alliance Scholarship. Finally, we are grateful to “Proyectos Basales y Vicerrectoría de Investigación, Desarrollo e Innovación”, 021742SG_PUBLIC. References: Almeida, L.C., García-Segura, S., Arias, C., Bocchi, N., Brillas, E., Electrochemical mineralization of the azo dye Acid Red 29 (Chromotrope 2R) by photoelectro – Fenton process (2012) Chemosphere, 89, pp. 751-758; Amaral, F.M., Kato, M.T., Florencio, L., Gavazza, S., Color, organic matter and sulfate removal from textile effluents by anaerobic and aerobic processes (2014) Bioresour. Technol., 163, pp. 364-369; APHA, AWWA, WPCF, Standard Methods for the Examination of Water and Wastewater (2012), 22th edition APHA Washington, D.C; Benito, A., Penadés, A., Lliberia, J.L., Gonzalez-Olmos, R., Degradation pathways of aniline in aqueous solutions during electro-oxidation with BDD electrodes and UV/H2O2 treatment (2017) Chemosphere, 166, pp. 230-237; Brillas, E., Martínez-Huitle, C.A., Decontamination of wastewaters containing synthetic organic dyes by electrochemical methods. An updated review (2015) Appl. Catal. B Environ., 166-167, pp. 603-643; Brillas, E., Sires, I., Oturan, M., Electro-Fenton process and related electrochemical technologies based on Fenton's reaction chemistry (2009) Chem. Rev., 109 (12), pp. 6570-6631; Chiavola, A., Farabegoli, G., Antonetti, F., Biological treatment of olive mill wastewater in a sequencing batch reactor (2014) Biochem. Eng. J., 85, pp. 71-78; Clesceri, L., Greenberg, A., Eaton, A., Standard Methods for Examination of Water & Wastewater. 21st edición (2005); El-Ghenymy, A., Cabot, P.L., Centellas, F., Garrido, J.A., Rodríguez, R.M., Arias, C., Brillas, E., Mineralization of sulfanilamide by electro-Fenton and solar photoelectro-Fenton in a pre-pilot plant with a Pt/air-diffusion cell (2013) Chemosphere, 91, pp. 1324-1331; El-Ghenymy, A., Centellas, F., Rodríguez, R.M., Cabot, P.L., Garrido, J.A., Sirés, I., Brillas, E., Comparative use of anodic oxidation, electro-Fenton and photoelectro-Fenton with Pt or boron-doped diamond anode to decolorize and mineralize Malachite Green oxalate dye (2015) Electrochim. Acta, 182, pp. 247-256; Espinoza, C., Romero, J., Villegas, L., Cornejo-Ponce, L., Salazar, R., Mineralization of the textile dye acid yellow 42 by solar photoelectro-Fenton in a lab-pilot plant (2016) J. Hazard. Mater., 319, pp. 24-33; García-Rodríguez, O., Bañuelos, J.A., El-Ghenymy, A., Godínez, L.A., Brillas, E., Rodríguez-Valadez, F.J., Use of a carbon felt–iron oxide air-diffusion cathode for the mineralization of Malachite Green dye by heterogeneous electro-Fenton and UVA photoelectro-Fenton processes (2016) J. Electroanal. Chem., 767, pp. 40-48; García-Segura, S., Salazar, R., Brillas, E., Mineralization of phthalic acid by solar photoelectro-Fenton with a stirred boron-doped diamond/air-diffusion tank reactor: influence of Fe3 + and Cu2 + catalysts and identification of oxidation products (2013) Electrochim. Acta, 113, pp. 609-619; García-Segura, S., Vieira dos Santos, E., Martínez-Huitle, C.A., Role of sp3/sp2 ratio on the electrocatalytic properties of boron-doped diamond electrodes: a mini review (2015) Electrochem. Commun., 59, pp. 52-55; García-Segura, S., Brillas, E., Cornejo-Ponce, L., Salazar, R., Effect of the Fe3 +/Cu2 + ratio on the removal of the recalcitrant oxalic and oxamic acids by electro-Fenton and solar photoelectro-Fenton (2016) Sol. Energy, 124, pp. 242-253; García-Segura, S., Anotai, J., Singhadech, S., Lu, M.-C., Enhancement of biodegradability of o-toluidine effluents by electro-assisted photo-Fenton treatment (2017) Process Saf. Environ. Prot., 106, pp. 60-67; Giraldo-Aguirre, L., Erazo-Erazo, E.D., Flórez-Acosta, O.A., Serna-Galvis, E.A., Torres-Palma, R.A., TiO2 photocatalysis applied to the degradation and antimicrobial activity removal of oxacillin: evaluation of matrix components, experimental parameters, degradation pathways and identification (2015) J. Photochem. Photobiol. A Chem., 311, pp. 95-103; Ikumi, S., Harding, T.H., Ekama, G.A., Biodegradability of wastewater and activated sludge organics in anaerobic digestion (2014) Water Res., 56, pp. 267-279; Inyang, M., Flowers, R., McAvoy, D., Dickenson, E., Biotransformation of trace organic compounds by activated sludge from a biological nutrient removal treatment system (2016) Bioresour. Technol., 216, pp. 778-784; Katzung, B.G., Masters, S.B., Trevor, A.J., Farmacología Básica y Clínica (2013), 12th edición Mc Graw Hill; Kemper, N., Veterinary antibiotics in the aquatic and terrestrial environment (2008) Ecol. Indic., 8, pp. 1-13; Kim, K.-S., Yang, C.-S., Mok, Y.S., Degradation of veterinary antibiotics by dielectric barrier discharge plasma (2013) Chem. Eng. J., 219, pp. 19-27; Kummerer, K., The presence of pharmaceuticals in the environment due to human use-present knowledge and future challenges (2009) J. Environ. Manag., 90, pp. 2354-2366; Markis, F., Baudez, J.C., Parthasarathy, R., Slatter, P., Eshtiaghi, N., Rheological characterization of primary and secondary sludge: impact of solids concentration (2014) Chem. Eng. J., 47, pp. 5493-5510; Martínez-Huitle, C.A., Rodrigo, M.A., Sires, I., Scialdone, O., Single and coupled electrochemical processes and reactors for the abatement of organic water pollutants: a critical review (2015) Chem. Rev., 115, pp. 13362-13407; Montalvo, S., Lorna, G., Tratamiento anaerobio de residuos. Universidad Técnica Federico Santa María 1st edition (2003); Moreira, F.C., Boaventura, R.A.R., Brillas, E., Vilar, V.J.P., Remediation of a winery wastewater combining aerobic biological oxidation and electrochemical advanced oxidation processes (2015) Water Res., 75, pp. 95-108; Olvera-Vargas, H., Oturan, N., Oturan, M.A., Brillas, E., Electro-Fenton and solar photoelectro-Fenton treatments of the pharmaceutical ranitidine in pre-pilot flow plant scale (2015) Sep. Purif. Technol., 146, pp. 127-135; Pereira, G.F., El-Ghenymy, A., Thiam, A., Carlesi, C., Eguiluz, K.I.B., Salazar-Banda, G.R., Brillas, E., Effective removal of Orange-G azo dye from water by electro-Fenton and photoelectro-Fenton processes using a boron-doped diamond anode (2016) Sep. Purif. Technol., 160, pp. 145-151; Pérez, J.F., Llanos, J., Sáez, C., López, P., Cañizares, P., Rodrigo, M.A., Treatment of real effluents from the pharmaceutical industry: a comparison between Fenton oxidation and conductive-diamond electro-oxidation (2017) J. Environ. Manag., 195, pp. 216-223; Pignatello, J.J., Oliveros, E., MacKay, A., Advanced oxidation processes for organic contaminant destruction based on the Fenton reaction and related chemistry (2006) Crit. Rev. Environ. Sci. 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PY - 2018

Y1 - 2018

N2 - The elimination of the antibiotic Nafcillin (NAF), which is usually used in hospitals and veterinary clinics around the world, was assessed through a combination of three advanced electrochemical oxidation processes followed by anaerobic digestion process. In the first stage different electrochemical advanced oxidation processes (EAOPs) were used: electro-oxidation with hydrogen peroxide (EO-H2O2), electro-Fenton (EF) and Photo electro-Fenton (PEF). After PEF, almost complete and highly efficient degradation and elimination of NAF was achieved, with the concomitant elimination of the associated antimicrobial activity. The fast degradation rate produced by PEF is explained by the oxidative action of hydroxyl radicals (•OH) together with the direct UV photolysis of complexes formed between Fe3 + and some organic intermediates. Total removal of NAF occurs after 90 min of electrolysis by PEF, with the generation of organic intermediates that remain in solution. However, when this post PEF process solution was treated with an anaerobic biological process, the intermediates generated in the electrochemical degradation of NAF were completely eliminated after 24 h. The kinetic degradation of NAF as well as the identification/quantification of products and intermediates formed during the degradation of antibiotic, such as inorganic ions, carboxylic acids and aromatic compounds, were determined by chromatographic and photometric methods. Finally, an oxidation pathway is proposed for the complete conversion to CO2. © 2017

AB - The elimination of the antibiotic Nafcillin (NAF), which is usually used in hospitals and veterinary clinics around the world, was assessed through a combination of three advanced electrochemical oxidation processes followed by anaerobic digestion process. In the first stage different electrochemical advanced oxidation processes (EAOPs) were used: electro-oxidation with hydrogen peroxide (EO-H2O2), electro-Fenton (EF) and Photo electro-Fenton (PEF). After PEF, almost complete and highly efficient degradation and elimination of NAF was achieved, with the concomitant elimination of the associated antimicrobial activity. The fast degradation rate produced by PEF is explained by the oxidative action of hydroxyl radicals (•OH) together with the direct UV photolysis of complexes formed between Fe3 + and some organic intermediates. Total removal of NAF occurs after 90 min of electrolysis by PEF, with the generation of organic intermediates that remain in solution. However, when this post PEF process solution was treated with an anaerobic biological process, the intermediates generated in the electrochemical degradation of NAF were completely eliminated after 24 h. The kinetic degradation of NAF as well as the identification/quantification of products and intermediates formed during the degradation of antibiotic, such as inorganic ions, carboxylic acids and aromatic compounds, were determined by chromatographic and photometric methods. Finally, an oxidation pathway is proposed for the complete conversion to CO2. © 2017

KW - Anaerobic digestion

KW - Antimicrobial activity

KW - Degradation

KW - Hydroxyl radical

KW - Livestock industry

KW - Nafcillin

KW - Photoelectro-Fenton process

KW - Agriculture

KW - Antibiotics

KW - Coal tar

KW - Electrochemical oxidation

KW - Electrooxidation

KW - Iron alloys

KW - Microorganisms

KW - Oxidation

KW - Oxidation resistance

KW - Photodegradation

KW - Photolysis

KW - Anaerobic digestion process

KW - Anti-microbial activity

KW - Electrochemical advanced oxidation process

KW - Electrochemical degradation

KW - Hydroxyl radicals

KW - Organic intermediates

KW - hydrogen peroxide

KW - nafcillin

KW - anaerobic digestion

KW - antibiotics

KW - antimicrobial activity

KW - degradation

KW - electrochemistry

KW - electrokinesis

KW - hydroxyl radical

KW - livestock

KW - oxidation

KW - photolysis

KW - pollutant removal

KW - water pollution

KW - Article

KW - chemical reaction

KW - controlled study

KW - degradation kinetics

KW - electrolysis

KW - mineralization

KW - oxidation kinetics

KW - photoelectro Fenton process

KW - priority journal

KW - quantitative analysis

KW - ultraviolet radiation

KW - waste component removal

U2 - 10.1016/j.scitotenv.2017.12.159

DO - 10.1016/j.scitotenv.2017.12.159

M3 - Article

VL - 624

SP - 1095

EP - 1105

JO - Science of the Total Environment

T2 - Science of the Total Environment

JF - Science of the Total Environment

SN - 0048-9697

ER -