• 391 Citations
  • 10 h-Index
20042017
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Research Output 2004 2017

  • 391 Citations
  • 10 h-Index
  • 14 Article
  • 2 Chapter
  • 1 Book
2017
1 Citations

IKD Current in cold transduction and damage-triggered cold hypersensitivity: Advances in Experimental Medicine and Biology

González, A., Herrera, G., Ugarte, G., Restrepo, C., Piña, R., Orio, P., Madrid Montecinos, R. L. & Pertusa Pastor, M. 2017 Springer New York LLC. 13 p.

Research output: Book/ReportBook

Biomedical Research
Sensory Receptor Cells
Kv1.1 Potassium Channel
Thermoreceptors
Neurons
4 Citations

Role of the excitability brake potassium current IKD in cold allodynia induced by chronic peripheral nerve injury

González, A., Ugarte, G., Restrepo, C., Herrera, G., Piña, R., Gómez-Sánchez, J. A., Orio, P., Madrid Montecinos, R. L. & Pertusa Pastor, M., 2017, In : Journal of Neuroscience. 37, 12, p. 3109-3126 18 p.

Research output: Contribution to journalArticle

Peripheral Nerve Injuries
Hyperalgesia
Potassium
Neurons
Constriction
2016
11 Citations

Targeted overexpression of tumor necrosis factor-α increases cyclin-dependent kinase 5 activity and TRPV1-dependent Ca2+ influx in trigeminal neurons

Rozas, P., Lazcano, P., Piña, R., Cho, A., Terse, A., Gonzalez-Billault, C., Kulkarni, A. B., Utreras, E., Madrid Montecinos, R. L. & Pertusa Pastor, M., 2016, In : Pain. 157, 6, p. 1346-1362 17 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase 5
Tumor Necrosis Factor-alpha
Neurons
Trigeminal Ganglion
Facial Pain
2015

Modulation of TRP channels by N-glycosylation and phosphorylation

Pertusa, M. & Madrid, R. 24 Aug 2015 TRP Channels in Sensory Transduction. Springer International Publishing, p. 73-96 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Transient Receptor Potential Channels
post-translational modification
glycosylation
Glycosylation
phosphorylation
2 Citations

Time-resolved neurite mechanics by thermal fluctuation assessments

Gárate, F., Betz, T., Pertusa, M. & Bernal, R., 30 Dec 2015, In : Physical Biology. 12, 6, 066020

Research output: Contribution to journalArticle

Neurites
Mechanics
Hot Temperature
Spectrum Analysis
Axons
3 Citations

TRP channels in cold transduction

González, A., Ugarte, G., Piña, R., Pertusa, M. & Madrid, R. 24 Aug 2015 TRP Channels in Sensory Transduction. Springer International Publishing, p. 185-207 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

sensory neurons
Sensory Receptor Cells
Thermoreceptors
neurons
Transient Receptor Potential Channels
2014
13 Citations

Bidirectional modulation of thermal and chemical sensitivity of TRPM8 channels by the initial region of the N-terminal domain

Pertusa, M., González, A., Hardy, P., Madrid, R. & Viana, F., 8 Aug 2014, In : Journal of Biological Chemistry. 289, 32, p. 21828-21843 16 p.

Research output: Contribution to journalArticle

Menthol
Hot Temperature
Modulation
10 Citations

Intimacies and Physiological Role of the Polymodal Cold-Sensitive Ion Channel TRPM8

Madrid, R. & Pertusa, M., 2014, In : Current Topics in Membranes. 74, 1, p. 293-324 32 p.

Research output: Contribution to journalArticle

Ion Channels
Transient Receptor Potential Channels
Menthol
Temperature
Sensory Receptor Cells
2012
39 Citations

N-glycosylation of TRPM8 ion channels modulates temperature sensitivity of cold thermoreceptor neurons

Pertusa, M., Madrid, R., Morenilla-Palao, C., Belmonte, C. & Viana, F., 25 May 2012, In : Journal of Biological Chemistry. 287, 22, p. 18218-18229 12 p.

Research output: Contribution to journalArticle

Thermoreceptors
Glycosylation
Ion Channels
Neurons
Chemical activation
2009
37 Citations

Differential role of the menthol-binding residue Y745 in the antagonism of thermally gated TRPM8 channels

Malkia, A., Pertusa, M., Fernández-Ballester, G., Ferrer-Montiel, A. & Viana, F., 3 Nov 2009, In : Molecular Pain. 5, 62

Research output: Contribution to journalArticle

1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole
Menthol
Econazole
Clotrimazole
Binding Sites
68 Citations

Lipid raft segregation modulates TRPM8 channel activity

Morenilla-Palao, C., Pertusa, M., Meseguer, V., Cabedo, H. & Viana, F., 3 Apr 2009, In : Journal of Biological Chemistry. 284, 14, p. 9215-9224 10 p.

Research output: Contribution to journalArticle

Menthol
Lipids
Sensory Receptor Cells
Temperature
Thermoreceptors
2008
55 Citations

Expression of GDNF transgene in astrocytes improves cognitive deficits in aged rats

Pertusa, M., García-Matas, S., Mammeri, H., Adell, A., Rodrigo, T., Mallet, J., Cristòfol, R., Sarkis, C. & Sanfeliu, C., Sep 2008, In : Neurobiology of Aging. 29, 9, p. 1366-1379 14 p.

Research output: Contribution to journalArticle

Glial Cell Line-Derived Neurotrophic Factor
Transgenes
Astrocytes
Lyssavirus
Aptitude
2007
73 Citations

Astrocytes aged in vitro show a decreased neuroprotective capacity

Pertusa, M., García-Matas, S., Rodríguez-Farré, E., Sanfeliu, C. & Cristòfol, R., May 2007, In : Journal of Neurochemistry. 101, 3, p. 794-805 12 p.

Research output: Contribution to journalArticle

Astrocytes
Glutamic Acid
Aging of materials
Proteins
Amino Acid Transport System X-AG
22 Citations

Transcriptional control of cholesterol biosynthesis in schwann cells by axonal neuregulin 1

Pertusa, M., Morenilla-Palao, C., Carteron, C., Viana, F. & Cabedo, H., 28 Sep 2007, In : Journal of Biological Chemistry. 282, 39, p. 28768-28778 11 p.

Research output: Contribution to journalArticle

Neuregulins
Neuregulin-1
Schwann Cells
Biosynthesis
Myelin Sheath
2006
9 Citations

Carboxyl-terminal fragment of amyloid precursor protein and hydrogen peroxide induce neuronal cell death through different pathways

Sebastià, J., Pertusa, M., Vílchez, D., Planas, A. M., Verbeek, R., Rodríguez-Farré, E., Cristòfol, R. & Sanfeliu, C. Dec 2006 In : Journal of Neural Transmission. 113, 12, p. 1837-1845 9 p.

Research output: Contribution to journalArticle

Amyloid beta-Protein Precursor
Hydrogen Peroxide
Cell Death
Apoptosis
Heme Oxygenase-1
2004
17 Citations

Down's syndrome astrocytes have greater antioxidant capacity than euploid astrocytes

Sebastià, J., Cristòfol, R., Pertusa, M., Vílchez, D., Torán, N., Barambio, S., Rodríguez-Farré, E. & Sanfeliu, C. Nov 2004 In : European Journal of Neuroscience. 20, 9, p. 2355-2366 12 p.

Research output: Contribution to journalArticle

Down Syndrome
Astrocytes
Antioxidants
Hydrogen Peroxide
Neurons
27 Citations

Neurotoxic effects of trimethyltin and triethyltin on human fetal neuron and astrocyte cultures: A comparative study with rat neuronal cultures and human cell lines

Cristòfol, R. M., Gassó, S., Vílchez, D., Pertusa, M., Rodríguez-Farré, E. & Sanfeliu, C. 30 Aug 2004 In : Toxicology Letters. 152, 1, p. 35-46 12 p.

Research output: Contribution to journalArticle

Cell culture
Astrocytes
Neurons
Rats
Cells